Allakos News


Allakos Secures $100 Million In Series B Financing

-- Proceeds will support advancement of AK002 in five disease areas --

-- Lead clinical program evaluating AK002 in eosinophilic gastroenteritis, an inflammatory gastrointestinal disease --


Press Release

SAN CARLOS, Calif., December 13, 2017– Allakos Inc., a private, clinical-stage biopharmaceutical company focused on the development of antibodies for the treatment of allergic, inflammatory and proliferative diseases, today announced the successful completion of a $100 million Series B equity financing. The Series B was led by New Enterprise Associates (NEA) and included Redmile Group, Partner Fund Management, Rock Springs Capital, LifeSci Venture Partners, Samsara BioCapital, and a large institutional investor, as well as existing investors Alta Partners, RiverVest Venture Partners, Roche Venture Fund, and 3X5 Partners. Paul Walker, a Partner at NEA, will join the Company’s Board of Directors.

Proceeds from the financing will be used to advance Allakos’s development programs including the Company’s lead clinical candidate, AK002, which is being evaluated in patients with eosinophilic gastritis, indolent systemic mastocytosis (ISM), urticaria and severe allergic conjunctivitis. This investment also will support Allakos’s preclinical programs.

“We are excited to welcome a distinguished group of new investors to Allakos and appreciate the support of our existing investors,” said Robert Alexander, Ph.D., and Chief Executive Officer of Allakos. “The Allakos team is committed to developing antibodies to potentially treat a broad range of conditions for which there are no approved therapies or where treatment options come with undesirable side effects. We have made tremendous progress during 2017 and, with this financing, we look forward to continuing the development of AK002 and our preclinical programs.”

“Allakos’s highly differentiated approach has the potential to deliver first-in-class treatments for serious illnesses affecting both large and rare disease populations,” said Paul Walker. “I welcome the opportunity to work with the experienced leadership team at Allakos as they conduct clinical trials in several important disease indications.”

About Allakos

Allakos is a privately held clinical-stage company developing antibodies that target immunomodulatory receptors present on the surface of immune effector cells involved in allergic, inflammatory, and proliferative diseases. The Company’s lead antibody, AK002, targets Siglec-8, an inhibitory receptor expressed on the surface of mast cells and eosinophils. AK002 has completed two Phase 1 studies, one in healthy volunteers and a single ascending dose study in patients with ISM. In addition, patients with ISM are currently being treated with AK002 for up to 12 months in a repeat dose study. In these studies, AK002 was well tolerated and demonstrated pharmacological activity on objective measures as well as patient reported symptoms.

For more information, please visit the Company's website at www.Allakos.com.

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Source: Allakos, Inc.

Investor Contact
Adam Tomasi, COO, CFO
investors@allakos.com
650.597.5002

Media Contact
Denise Powell
denise@redhousecomms.com
510.703.9491



Allakos Announces Additions to Senior Leadership Team

-- Board of Directors appoints Robert Alexander as CEO and Adam Tomasi as COO & CFO --

-- Allakos plans to initiate a broad, multi-indication clinical program with AK002 in 2017 --


Press Release

SAN CARLOS, Calif., August 15, 2017 – Allakos Inc., a private, clinical-stage biopharmaceutical company focused on the development of therapeutic antibodies for the treatment of allergic, inflammatory and proliferative diseases, today announced the appointments of two industry veterans to the leadership team. Dr. Robert Alexander, former Chief Executive Officer of ZS Pharma, has been appointed as Chief Executive Officer (CEO) of Allakos and Dr. Adam Tomasi, former Chief Scientific Officer and Head of Corporate Development at ZS Pharma, has been appointed as Chief Operating Officer (COO) and Chief Financial Officer (CFO) of Allakos.

“We are extremely pleased with the addition of Robert and Adam to the Allakos leadership team; they are executives who have successfully advanced drug candidates into and through clinical development, built successful organizations, and delivered value to investors,” said Dan Janney, a Managing Director at Alta Partners and Chairman of the Allakos Board. “Having Robert and Adam in key leadership positions will help the company bring its novel antibody therapeutics to patients and realize the company’s potential. On behalf of the Board of Directors, I want to thank Dr. Christopher Bebbington, who cofounded Allakos, for his leadership in progressing AK002 from target discovery to clinical development. Chris will continue at Allakos and will focus on the development of the company’s therapeutic antibody pipeline.”

Dr. Alexander added, “By selectively targeting eosinophils and mast cells, AK002 has the potential to treat a number of serious allergic and inflammatory diseases. Many of these diseases have no approved treatments or continue to have significant unmet need. AK002 has demonstrated safety and activity in Phase 1 clinical trials and I’m looking forward to advancing its development.”

About Dr. Alexander

Dr. Alexander has contributed to the leadership and success of several biotechnology companies. Most recently, he was CEO of ZS Pharma where he led the initial public offering and sale of ZS Pharma to AstraZeneca. Prior to ZS Pharma, Dr. Alexander was a Director at Alta Partners, a venture capital firm specializing in investing in development stage therapeutic companies. During his time at Alta Partners, he led investments in SARcode Biosciences and Lumena Pharmaceuticals (both acquired by Shire), ZS Pharma (acquired by AstraZeneca) and Allakos. Prior to Alta Partners, Dr. Alexander was a Principal in MPM Capital’s BioEquities Fund and worked in the Business Development group at Genentech. He holds a Ph.D. in immunology from the University of North Carolina at Chapel Hill and a Bachelor’s degree in zoology from Miami University of Ohio.

About Dr. Tomasi

Prior to joining Allakos, Dr. Tomasi was Chief Scientific Officer and Head of Corporate Development at ZS Pharma where he led scientific, business development, and investor relations functions through the Company’s initial public offering and sale to AstraZeneca. Before joining ZS Pharma, Dr. Tomasi was a Principal at Alta Partners where he contributed to investments in ZS Pharma (acquired by AstraZeneca), Lumena Pharmaceuticals (acquired by Shire), Excaliard (acquired by Pfizer), ChemGenex (acquired by Cephalon), and Allakos. Dr. Tomasi served as a drug discovery scientist with Gilead Sciences and Cytokinetics. He holds an M.B.A. from the Harvard-MIT Biomedical Enterprise Program, a bachelor’s degree in chemistry from the University of California, Berkeley and a Ph.D. in chemistry from the University of California, Irvine.

About Allakos

Allakos is a privately held clinical-stage company developing antibodies that target immunomodulatory receptors present on the surface of immune effector cells involved in allergic, inflammatory, and proliferative diseases. The Company’s lead antibody, AK002, targets Siglec-8, an inhibitory receptor expressed on the surface of mast cells and eosinophils. AK002 has completed two Phase 1 human studies, one in healthy volunteers and one in patients with indolent systemic mastocytosis. In these studies, AK002 was well tolerated and demonstrated pharmacological activity on objective measures as well as patient reported symptoms.

For more information, please visit the Company's website at www.Allakos.com.

###
Source: Allakos, Inc.

Investor Contact
Adam Tomasi, COO, CFO
investors@allakos.com
650.597.5002

Media Contact
Denise Powell
denise@redhousecomms.com
510.703.9491