Novel Biology

developing therapeutic antibodies targeting Siglec receptors

Lead Programs Focused on Inhibiting Mast Cell and/or Eosinophil Activation

mast cells and eosinophils are pathogenic in a number of inflammatory diseases

Lirentelimab (AK002)

an investigational monoclonal antibody that depletes eosinophils and inhibits mast cells

AK006

an investigational monoclonal antibody that selectively and potently inhibits mast cells, including KIT mediated signaling